Dimitra Kalavrizioti, Anastassios Vourekas, A. Tekos
Mar 1, 2003
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Influential Citations
6
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Quality indicators
Journal
Molecular Biology Reports
Abstract
A cell-free system derived from Dictyostelium discoideum has been used to study the kinetics of inhibition of RNase P by puromycin, amicetin and blasticidin S. Detailed kinetic analysis showed that the type of inhibition of RNase P activity by puromycin is simple competitive, whereas the type of inhibition by amicetin and blasticidin S is simple non-competitive. On the basis of Ki values amicetin is stronger inhibitor than puromycin and blasticidin S.