A. Jadhav, W. Liang, J. Balsevich
May 1, 2012
Citations
0
Influential Citations
14
Citations
Quality indicators
Journal
British Journal of Pharmacology
Abstract
BACKGROUND AND PURPOSE L‐tryptophan (L‐W) is a precursor of the vasoconstrictor, 5‐HT. However, acute administration of L‐W ethyl ester (L‐Wee) lowered blood pressure. The mechanism of action is unknown. This study compares the vascular effects of L‐W and L‐Wee in intact animals, isolated aortic rings, small mesenteric arteries (MA) and explores possible mechanisms by studies in vascular smooth muscle cells (VSMC) of MA.