Yu. I. Laz'yan, A. I. Bokanov, V. Kuzovkin
Dec 1, 1994
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Journal
Pharmaceutical Chemistry Journal
Abstract
The 2,2,6,6-tetrachlorocyclohexanone (TCC) (I) is utilized for the synthesis of 2,6-dichlorobenzonitrile, which is a herbicide [1], dichlorophenol, which can be used as the basis for the synthesis of more than 10 practically important chemical substances [2], as well as for the synthesis of 2,6-dichloroaniline and 2,6-dichlorodiphenylamine [3] key intermediates in the production of the medicinal preparations klofelin and ortofen. The TCC is obtained by the chlorination of cyclohexanone in the solution of carbon tetrachloride or in the melt of TCC itself, with the mp 80-84~ [1, 2].