X. Shui, D. Eggleston
May 15, 1995
Citations
0
Influential Citations
3
Citations
Journal
Acta Crystallographica Section C-crystal Structure Communications
Abstract
The structures of two new forms of lasalocid sodium salt, sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl)tetrahydro-3S-methyl-2S-furanyl}-4S-hydroxy-3R,5S-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoate (A), Na + .C 34 H 53 O 8 − , and sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl)tetrahydro-3S-methyl-2S-furanyl}-4S-hydroxy-3R,5S-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoate diethyl ether solvate (B), Na + .C 34 H 53 O 8 − .C 4 H 10 O, are reported. Form A exist as a «head-to-head» dimer, while form B is a «head-to-tail» dimer. Sodium is coordinated to six O atoms from the lasalocid anion in both forms, but the coordination spheres differ. Form A contains a bridging carbonyl O atom, but, remarkably, the carboxylate group does not coordinate to the sodium ion. In form B, the carbonyl O atom does not bridge but there is a direct carboxylate-sodium interaction