K. Kinnamon, E. Steck, P. S. Loizeaux
Mar 1, 1980
Citations
0
Influential Citations
4
Citations
Quality indicators
Journal
American journal of veterinary research
Abstract
Members of a class of compounds designated lepidines (8-amino-6-methoxy-4-methylquinoline derivatives) were tested in a hamster-Leishmania donovani model and found to have activity many-fold that of a reference drug meglumine antimoniate. One of them, 8-(7-isopropylaminoheptylamino)-6-methoxy-4-methylquinoline, was found to be 138 times as effective as the standard antimonial drug used.