Michael L. Jones, L. Kuyper, V. L. Styles
Nov 1, 1994
Citations
0
Influential Citations
7
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
The mild preparation of N-cyano-N-(1-H-indol-5-yl)guanidine and its cyclization to 1,3-diamino-7H-pyrrolo[3,2-f]quinazoline is described. Whereas previously reported methods of cyclization employed high temperatures to effect ring closure, we found that certain Lewis acids, such as boron trifluoride etherate, induce cyclization at moderate temperatures.