Ying Han, K. Ebinger, Lauren E. Vandevier
Jan 27, 2010
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron Letters
Abstract
A new, divergent, efficient, and selective synthesis of furo- and thieno[2,3-d]pyrimidin-4-amine derivatives by microwave irradiation has been developed starting from readily available amines and substituted 2-aminofuran-3-carbonitrile or 2-aminothiophene-3-carbonitrile, which are converted into corresponding formamidines in DMF using benzenesulfonyl chloride.