C. Willans, Jan M. C. A. Mulders, J. G. Vries
Dec 7, 2003
Citations
0
Influential Citations
48
Citations
Journal
Journal of Organometallic Chemistry
Abstract
A range of substituted aryl bromides were coupled with methyl 2-acetamido acrylate using ligand-free palladium catalysis. Subsequently asymmetric hydrogenation with Rh/MonoPhos yielded substituted phenylalanines in high enantioselectivities (e.e. 92-99%).