M. Falorni, C. Collu, S. Conti
1996
Citations
0
Influential Citations
29
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract Starting from l -serine and l -threonine, (S)-diphenyl-(2,2-dimethyl-1,3-oxazolidin-4-yl)-methanol and (4S,5R)-diphenyl-(2,2-dimethyl-5-methyl-1,3-oxazolidin-4-yl)-methanol were prepared in good yields. The use of these compounds as very efficient chiral catalysts for the enantioselective addition of diethylzinc to aldehydes is described. This paper reports the first example of the use of oxazolidine methanols in asymmetric synthesis.