Erin Wachter, D. Heidary, B. Howerton
Aug 29, 2012
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Influential Citations
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Quality indicators
Journal
Chemical communications
Abstract
Incorporation of biquinoline ligands into Ru(II) polypyridyl complexes produces light-activated systems that eject a ligand and photobind DNA after irradiation with visible and near-IR light. Structural analysis shows that distortion facilitates the photochemistry, and gel shift and cytotoxicity studies prove the compounds act as anti-cancer photodynamic therapy (PDT) agents in the tissue penetrant region.