Xue-mei Gao, J. Pu, Sheng-Xiong Huang
Feb 16, 2008
Citations
3
Influential Citations
54
Citations
Quality indicators
Journal
Journal of natural products
Abstract
Phytochemical investigation of Kadsura angustifolia led to the isolation and identification of 26 lignans and two triterpenoids, including 11 new lignans named kadangustins A-K ( 1- 11). The structures and stereochemistry of 1- 11 were elucidated by analysis of spectroscopic data. Except for 11 and 20, all the lignans were evaluated for their inhibitory activity against HIV-1. Binankadsurin A ( 19) showed anti-HIV activity with an EC 50 value of 3.86 microM.