M. Filice, R. Vanna, M. Terreni
Jul 1, 2009
Citations
0
Influential Citations
10
Citations
Journal
European Journal of Organic Chemistry
Abstract
A highly efficient regioselective enzymatic preparation ofpenta-O-acetyl-1,5-anhydro-2-deoxy-3-hydroxy-4-O-β-galactopyranosyl-D-arabinohex-1-enitol has been successfully performed for the first time. This product was obtained in >99 % conversion (>95 % overall yield) by hydrolysis of per-O-acetylated lactal catalyzed by the lipase from Rhizomucor miehei immobilized on octylagarose. This molecule could be a potential building block for efficient synthesis of oligosaccharides or glycoconjugates.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)