J. Marshall, H. Chobanian, Mathew M. Yanik
Sep 25, 2001
Citations
0
Influential Citations
29
Citations
Journal
Organic letters
Abstract
[reaction: see text]. An improved procedure for the resolution of 4-trimethylsilyl-3-butyn-2-ol has been developed. The mesylate derivatives of the resolved alcohols have been found to undergo highly enantio-, regio-, and diastereoselective additions to aldehydes, leading to homopropargylic alcohol adducts.