Cecilia Gómez, F. Huerta, M. Yus
Jan 27, 1997
Citations
0
Influential Citations
19
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The reaction of 2-, 3- or 4-chlorobenzyl chlorides ( 1a-c ) with an excess of lithium and a catalytic amount of DTBB (7 mol%) in the presence of different electrophiles [Pr i CHO, Bu t CHO, Et 2 CO, (CH 2 ) 5 CO, PhCOMe, Me 3 SiCl] in THF at −50°C leads after hydrolysis with water, to the expected dioles or disilylated compounds 2aa-2cf .