Hiromichi Tanaka, H. Hayakawa, S. Iijima
1985
Citations
0
Influential Citations
37
Citations
Journal
Tetrahedron
Abstract
Abstract Synthesis of 6-substituted 2'-deoxyuridines can be effected by lithiation of 3',5'- O -(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyuridine with LDA followed by the reaction of its lithio derivative with electrophiles. This method provides a general, regiospecific and simple route to various types of 6-substituted 2'-deoxyuridines which have, so far, been known to be difficult to prepare.