Gisbert Tuchalski, A. Hänsicke, G. Reck
Dec 6, 2007
Citations
0
Influential Citations
3
Citations
Journal
Acta Crystallographica Section E: Structure Reports Online
Abstract
The hydrochloride salt of chiral l-nebivolol {systematic name: (+)−(R,S,S,S)-bis[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]ammonium chloride dihydrate}, C22H26F2NO4 +·Cl−·2H2O, was obtained by chiral liquid chromatography as a dihydrate. The pyran rings adopt half-chair conformations. Hydrogen bonds between the cation, anions and water molecules contribute to the formation of layers parallel to the ac plane.