R. Robson, R. Bailey, K. Lynn
2012
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Quality indicators
Journal
Drugs
Abstract
Lomefloxacin is available in an oral dosage form as the hydrochloride salt and in the parenteral form as a mesylate salt. The absolute oral bioavailability o,f lomefloxacin is 98% in healthy volunteers (MorrIson & Mant 1990). The primary objective of the study was to investigate the pharmacokinetic profile of lomefloxacin after intravenous and oral administration in patients with acute pyelonephritis.