J. Turner, V. Hanly
Aug 30, 1947
Citations
0
Influential Citations
25
Citations
Journal
Nature
Abstract
SINCE Quastel and Whetham's discovery in 19251, biochemists have come to regard the malonate ion as one of the very few specific enzyme inhibitors—as a competitive inhibitor of succinic dehydrogenase2. Malonate has therefore been widely used with animal tissue, in work designed to elucidate the Krebs cycle. Recently it has also been applied to plant tissues, but with discordant results. Machlis3 showed that malonate inhibited part of the respiration of barley roots; but several other workers have independently stated that malonate does not inhibit and may even stimulate plant respiration4–7.