E. Pungor, M. Pécs, L. Szigeti
1984
Citations
0
Influential Citations
20
Citations
Journal
Analytica Chimica Acta
Abstract
Abstract A mass spectrometric method for monitoring 2-oxoglutarie acid (an essentially nonvolatile compound) in aqueous solutions is described. Silicone rubber membranes are used for mass spectrometric sampling; the acid is esterified with methanol. The assay was applied to monitoring 2-oxoglutarie acid in penicillin fermentation broths. Three ion peaks of the ester were suitable for measurements. Preliminary work on faster esterification with diazomethane in diethyl ether is reported.