E. Kimura, A. L. Albiero, R. Cuman
Apr 1, 2000
Citations
1
Influential Citations
13
Citations
Quality indicators
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Abstract
This study explored the interference by Maytenus aquifolium leaves hydroalcoholic (MALHE) extract, administered orally, on the pharmacokinetic and antiinflammatory activity of piroxicam in rats. The results showed no significant difference in piroxicam bioavailability with simultaneous application of MALHE. MALHE also had no effect on the inhibitory effect of piroxicam on inflammatory processes induced by carrageenan and complete Freund adjuvant.