JoAnne Stubbe, M. Ator, T. Krenitsky
Feb 10, 1983
Citations
1
Influential Citations
85
Citations
Quality indicators
Journal
The Journal of biological chemistry
Abstract
The 3'-carbon--hydrogen bond of [3'-3H]uridine 5'-diphosphate is cleaved during its conversion to 2'-deoxyuridine 5'-diphosphate catalyzed by Esherichia coli ribonucleoside diphosphate reductase. A selection against 3H of approximately 3.3 is observed on this reduction reaction. During the course of this reaction, a small but significant amount of 3H is released to the solvent.