C. D. Johnson, A. Katritzky, M. Viney
1967
Citations
0
Influential Citations
6
Citations
Journal
Journal of The Chemical Society B: Physical Organic
Abstract
Kinetic criteria show that the nitration of 3,5-dimethoxypyridine proceeds on the conjugate acid species in the 2-position, and that the 6-nitration of 3,5-dimethoxy-2-nitropyridine occurs on the free base. Relative reactivities are compared with the corresponding benzenoid compounds. A set of rules is proposed for the nitration of substituted pyridines and their synthetic applications discussed.