Z. Heng
2012
Citations
0
Influential Citations
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Citations
Quality indicators
Journal
Medical Journal of Chinese People's Health
Abstract
Objective:To explore the efficacy of Loxapine succinate in the treatment of schizophrenia.Methods:6 comparative studies of Loxapine succinate and the other antipsychotics in the treatment of schizophrenia were analyzed by meta-analysis in therapeutic effects and side effects.Results: The significant difference in change of symptom before and after treatment by Loxapine succinate was found,d=2.80,95% CI(2.55,3.05),x2=21.93,P0.01.Comparison between Loxapine succinate and the other antipsychotics at 2 weeks treatment and at the end of each trial showed that there was no significant difference with respect to the clinical efficacy.Conclusions: Loxapine succinate has a similar clinical efficacy compared with controlled antipsychotics.