J. Sinsheimer, E. Van den Eeckhout, L. Hewitt
May 1, 1976
Citations
0
Influential Citations
6
Citations
Journal
Journal of medicinal chemistry
Abstract
1-(3-Chlorophenyl)-2-(4-hydroxphenyl)-1-methyl-2(2-pyridine)ethanol (8a) has been synthesized and found to be the major urinary metabolite following intraperitoneal administration of 1-(3-chlorophenyl)-1-methyl-2-phenyl-2-(2-pyridine)ethanol (1) to rats. This metabolite has a hypocholesteremic effect in rats similar to that of the parent drug.