E. Boyland, G. Wiltshire
Feb 1, 1953
Citations
0
Influential Citations
13
Citations
Journal
The Biochemical journal
Abstract
The metabolism of naphthalene in animals was reviewed by Young (1950). Since that review was published experiments have shown that the oxidative pathways leading to 1-naphthol and to 1:2dihydroxy-1:2-dihydronaphthalene (naphthalenediol), are probably separate and independent (cf. Boyland & Wiltshire, 1952). The conversion of naphthalene to naphthalene mercapturic acid (Bourne & Young, 1934) probably involves still another metabolic route. The present experiments indicate that isolated slices of rat liver are able to oxidize naphthalene to naphthalenediol. EXPERIMENTAL