Guo-You Li, Bogang Li, Tao Yang
2008
Citations
0
Influential Citations
30
Citations
Quality indicators
Journal
Helvetica Chimica Acta
Abstract
Two new depsidones, mollicellins I and J (1 and 2, resp.), and a new chromone, 2-(hydroxymethyl)-6-methylmethyleugenin (3), along with six known compounds, 4-9, were isolated from the ethyl acetate extract of a solid-state fermented culture of Chaetomium brasiliense. Their structures were elucidated based on spectroscopic analysis. Mollicellins I and H (5) exhibited significant growth inhibitory activity against human breast cancer (Bre04), human lung (Lu04), and human neuroma (N04) cell lines with GI(50) values between 2.5-8.6 mu g/ml.