Ling-zhi Yuan, D. Renko, I. Khelifi
Jun 23, 2016
Citations
0
Influential Citations
9
Citations
Journal
Organic letters
Abstract
For the first time, the combination of chlorotrimethylsilane with NaI is used as a selective reducting system toward 1,2-diketones. This combination is successfully evaluated with several unsymmetrically benzil derivatives, which are reduced in good yields and with a total α-regioselectivity at room temperature. Identification of benzoin intermediates is achieved, and a mechanistic radical process is proposed.