Yang Wang, Ying Wang, Guo Zhenyu
Dec 1, 2016
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0
Influential Citations
34
Citations
Journal
Asian Journal of Organic Chemistry
Abstract
An oxidative C−H amination of 8-acylaminoquinolines and anilides with N-fluorobenzenesulfonimide (NFSI) has been developed. This process was mediated by a hypervalent iodine reagent PhI(OPiv)2 under mild reaction conditions without any metallic catalyst or oxidant. The protocol showed good air and moisture tolerance, functional groups compatibility, and gave the highly site-selective amination products in moderate to good yields, providing a novel and facile method for synthesis of arylamine compounds.