Hua Wang, Lina Guo, Xinhua Duan
Sep 27, 2013
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Influential Citations
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Quality indicators
Journal
Organic letters
Abstract
A metal-free oxidative spirocyclization of hydroxymethylacrylamide with 1,3-dicarbonyl compounds is described. The reaction proceeds through tandem dual C-H functionalization and intramolecular dehydration, in which two new C-C bonds and one C-O bond were formed. This method affords a novel and straightforward access to various spirooxindoles under mild conditions.