M. Cabiddu, S. Cabiddu, Enzo Cadoni
Apr 19, 2004
Citations
0
Influential Citations
6
Citations
Journal
Tetrahedron
Abstract
Abstract The metallation reaction of bromo(alkylthio)benzenes is described. The results show the complementarity of these reactions with the metal–hydrogen exchange reaction. In fact, monometallation of bromo(methylthio)benzenes afforded products substituted in para or meta or ortho to the thioethereal function while bimetallation led to αS,para, αS,meta and αS,ortho disubstituted products. Analogously, the monometallation of 4-bromo-(isopropylthio)benzene afforded para-monosubstituted and ortho,para-disubstituted products.