M. Fujihara, Masashi Kikuchi, Y. Kurimoto
May 1, 2006
Citations
2
Influential Citations
37
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Quality indicators
Journal
Japanese Journal of Ophthalmology
Abstract
BackgroundMethanol is a highly toxic substance used as an industrial solvent and automotive antifreeze. Human consumption of methanol may result in severe visual disturbances. Because optical coherence tomography (OCT) is very useful for evaluating retinal edema and nerve fiber swelling, we used OCT to examine a patient with methanol-induced retinal toxicity.CaseA 37-year-old man who drank industrial alcohol (100 ml/day) for 4 days.ObservationsThe retinal profiles were evaluated by OCT and fluorescein angiography during the course of treatment. OCT demonstrated peripapillary nerve fiber swelling and accumulation of intraretinal fluid in the acute phase. In the chronic phase, the retinal thickness was diffusely decreased. Steroid pulse therapy was not effective, and his visual acuity was 6/200 OD and 4/100 OS 2 years after the event.ConclusionOCT was very useful for evaluating the severity of the retinal edema and the temporal changes in the retinal profile. Jpn J Ophthalmol 2006;50:239–241 © Japanese Ophthalmological Society 2006