C. Kumar, B. Gurupadayya
Feb 15, 2013
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Influential Citations
9
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Journal
Biochemistry & Analytical Biochemistry
Abstract
Dimethoate (Figure 1) is a widely used organophosphate insecticide used to kill insects on contact. It was patented and introduced in the 1950s by American Cyanamid. Like other organophosphates, dimethoate is an anti-cholinesterase which disables cholinesterase, an enzyme essential for central nervous system function [1]. The literature survey, it was found that dimethoate estimated by analytical methods such reversed-phase high performance liquid chromatographic HPLC method [2] and some spectrophotometric methods like mass spectrophotometry. The HPLC method has its relative merits but the majority of them are carried out at elevated temperatures, time consuming, use relatively expensive reagents, involve extraction, use of buffer system. In this report, we present one simple, sensitive, cost-effective and accurate method for the determination of dimethoate [3].