K. Uoto, H. Takenoshita, T. Ishiyama
Dec 15, 1997
Citations
0
Influential Citations
4
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
We have developed a new method to modify the C-4 position of 10-deacetylbaccatin III (5) using the C-4 acetoxy anion of the 13-keto derivative (7) and various alkyl halides. The method developed herein should be very useful for the preparation of C-4 modified taxoid analogs.