Enrique Vazquez, I. Davies, J. Payack
Sep 18, 2002
Citations
0
Influential Citations
45
Citations
Journal
The Journal of organic chemistry
Abstract
2-Indolyl borates are prepared via addition of LDA to a mixture of N-Boc-indole and triisopropyl borate at 0-5 degrees C. Following acidic hydrolysis, the boronic acids are isolated by crystallization in good to excellent yield (73-99%). The method is quite general, tolerating a wide range of functional groups, and also provides access to 2-silyl derivatives (80-91%).