H. Naora, T. Ohnuki, A. Nakamura
Jul 1, 1988
Citations
0
Influential Citations
4
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
A useful prostanoid synthon, 7-(2-hydroxy-5-oxo-1-cyclopentenyl)heptanoic acid (3), was prepared from commercially available cyclooctanone in two steps. Nine other related cyclopentanoids which are also valuable synthons for prostaglandins were obtained from 3 in reasonable yields via several steps. The procedure is capable of generating these useful synthons on a laboratory scale.