Y. Sabutskii, S. Polonik, V. Denisenko
Jul 30, 2014
Citations
0
Influential Citations
6
Citations
Journal
Synthesis
Abstract
A series of N -acetyl- S -[(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl]- l -cysteine conjugates were obtained in good yields by acid-catalyzed condensation of substituted 2-hydroxy-1,4-naphthoquinones with N -acetyl- l -cysteine and paraformaldehyde. Based on this reaction, a first synthesis of fibrostatins B, C, and D was developed.