Joselyn Bogantes-Molina, G. Madrigal-Redondo, Lorena Berrocal-Barrantes
May 30, 2019
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Journal
GSC Biological and Pharmaceutical Sciences
Abstract
Metformin hydrochloride is a hypoglycemic agent used for type II Diabetes Mellitus treatment, and one of the most used to manage it. The objective of the present work was the development and validation of an analytical method to quantify metformin hydrochloride in the dissolution medium by UV spectrophotometry. Linearity and range, accuracy and precision were the validation process parameters. Validation process results showed the analytical method was easy, quick, secure and, furthermore, a linear, accurate and precise method in the studied concentrations range. Therefore, it is a reliable analytical method.