M. Iwao, Osamu Motoi
Aug 14, 1995
Citations
0
Influential Citations
29
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 1-Triisopropylsilylgramine methiodide reacted smoothly with a variety of nucleophiles in the presence of tetrabutylammmonium fluoride to give 3-substituted indoles. The 3,4-disubstituted indoles were efficiently synthesized by sequential use of 4-selective lithiation of 1-triisopropylsilylgramine and this new substitution reaction.