M. Periasamy, N. Kumar, S. Sivakumar
May 2, 2001
Citations
0
Influential Citations
25
Citations
Journal
The Journal of organic chemistry
Abstract
Resolution of the racemic amino alcohol derivatives 1-6 is readily achieved to obtain enantiomerically enriched compounds using chiral 1,1'-bi-2-naphthol and boric acid in solvents such as CH(3)CN, THF, and MeOH. Purification of the diastereomeric mixture 7 has also been carried out following this method. The corresponding intermediate ammonium borate complexes were also characterized by X-ray diffraction methods.