V. Vinogradov, I. Dalinger, S. Shevelev
2005
Citations
0
Influential Citations
5
Citations
Quality indicators
Journal
Pharmaceutical Chemistry Journal
Abstract
N-Aminopyrazoles have been known for about the past 30 years but their chemistry began to be developed fairly actively only in the early seventies when the first publications appeared on the oxidative conversion of N-aminopyrazoles into 1,2,3triazines. Interest in N-aminopyrazoles is also generated by their use as valuable intermediates in the synthesis of polycyclic heterocycles, which are biologically active substances and include analgesics and antidepressants. The accumulated data have not yet been systematized. Literature data up to 1992 and part of 1993 on pyrazoles having an NH 2 group on a ring nitrogen atom are summarized in the present review according to preparation, physicochemical properties, conversions, and applications.