H. Nagarajaiah, N. Begum
Nov 25, 2011
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Influential Citations
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Journal
Acta Crystallographica Section E: Structure Reports Online
Abstract
In the title compound, C24H22N2O6S, a pyrimidine ring substituted with 4-hydroxy-3-methoxyphenyl is fused with a thiazole ring. The 4-hydroxy-3-methoxyphenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)°. The pyrimidine ring adopts a twist boat conformation. In the crystal, O—H⋯N interactions result in a chain running along the b axis. The carbonyl O atom bonded to the thiazole ring is involved in two C—H⋯O hydrogen-bond interactions forming centrosymmetric dimers; the ten- and six-membered rings resulting from these interactions have R 2 2(10) and R 1 2(6) motifs, respectively.