Hanna Skarpos, D. V. Vorob'eva, S. Osipov
Sep 22, 2006
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0
Influential Citations
22
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Journal
Organic and Biomolecular Chemistry
Abstract
Convenient routes to methyl 2-oxalylimino- and 2-(phosphonoformimido)-3,3,3-trifluoropropanoates have been elaborated, based on the reaction of methyl trifluoropyruvate with ethyl oxamate or diethyl carbamoylphosphonate, respectively, followed by dehydration. The compounds obtained are useful synthetic intermediates toward a variety of novel 3,3,3-trifluoroalanine derivatives that are potential drug candidates.