O. Kitagawa, A. Hashimoto, Yoshiro Kobayashi
Aug 10, 1990
Citations
0
Influential Citations
20
Citations
Journal
Chemistry Letters
Abstract
2,2-Difluoroketene silyl acetal, generated in situ by treating methyl difluoroiodoacetate with Zn followed by chlorosilane, readily reacted with α,β-unsaturated carbonyl compounds or acetals to give the 1,4-addition products, preferentially. The difluoro analogs of glutamic acid and lysine were prepared through the present reaction.