Niraj K. Ladani, Divyesh C. Mungra, Manish P. Patel
Dec 1, 2011
Citations
0
Influential Citations
48
Citations
Journal
Chinese Chemical Letters
Abstract
Abstract Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[1,5- a ]quinoline-4-carbaldehyde, dimedone/cyclohexane-1,3-dione, ethyl/methyl acetoacetate and ammonium acetate was described as the preparation of tetrazolo[1,5- a ]quinoline based 1,4-dihydropyridines, acridine-1,8-diones and polyhydroquinolines. The process presented here is simple, rapid, environmentally welcoming and high yielding. All the derivatives were subjected to an in vitro antimicrobial screening against a representative panel of bacteria and fungi and results worth further investigations.