S. Kamila, E. Biehl
Aug 1, 2012
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron Letters
Abstract
Abstract (5Z,5′Z)-3,3′-(1,4-Phenylenebis(methylene)-bis-(5-arylidene-2-thioxothiazolidin-4-one) derivatives ( 5a – r ) have been synthesized by the condensation reaction of 3,3′-(1,4- or 1,3-phenylenebis(methylene))bis(2-thioxothiazolidin-4-ones) ( 3a , b ) with suitably substituted aldehydes (4a–f) or 2-(1 H -indol-3-yl)2-oxoacetaldehydes ( 8a – c ) under microwave conditions. The bis(2-thioxothiazolidin-4-ones) were prepared from the corresponding primary alkyl amines ( 1a , b ) and di-(carboxymethyl)-trithiocarbonyl ( 2 ). The 2-(1 H -indol-3-yl)-2-oxoacetaldehydes ( 8a – c ) were synthesized from the corresponding acid chlorides ( 7a – c ) using HSnBu 3 .