Wei‐Hai Chen, G. Luo, Qi Lei
Jan 11, 2015
Citations
2
Influential Citations
86
Citations
Quality indicators
Journal
Chemical communications
Abstract
Multifunctional Biotin-PEG-b-PLL(Mal)-peptide-DOX polymeric micelles were prepared to selectively eliminate cancer cells. The micelles were able to enhance cancer cell uptake via the receptor-mediated endocytosis and respond to the stimulus of cancer cell excessive secreted protease MMP-2 to release the anticancer drug and induce apoptosis of cancer cells in a targeted manner.