U. Bierbach, T. Hambley, N. Farrell
Jan 31, 1998
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0
Influential Citations
69
Citations
Journal
Inorganic Chemistry
Abstract
A new class of mono- and dinuclear platinum(II) complexes is described that derives from the cisplatin analogues [Pt(en)Cl2] and [Pt(dach)Cl2] (en = 1,2-ethanediamine, dach = racemic trans-1,2-cyclohexanediamine). The selective substitution of one chloro ligand in these species by 1,1,3,3-tetramethylthiourea (tmtu), which requires abstraction of chloride with silver salt in DMF, gives [PtCl(en)(tmtu)]NO3 (1) and [PtCl(dach)(tmtu)]NO3 (2). Similarly, reactions employing the novel bifunctional thiourea derivatives C2H4(NMeCSNMe2)2 (3) and C6H12(NMeCSNMe2)2 (4) yield the dinuclear complexes [{Pt(en)Cl}2(μ-3-S,S‘)](NO3)2 (5) and [{Pt(en)Cl}2(μ-4-S,S‘)](NO3)2·0.5EtOH (6), respectively. The compounds were characterized by 1H, 13C, and 195Pt NMR spectroscopy, elemental analyses, and IR data. 195Pt chemical shifts in the −2895 to −2929 ppm region confirm the mixed-donor [PtN2ClS] coordination for 1, 2, 5, and 6 and thiourea-S coordination in all cases. The single-crystal X-ray structures of 2−4 have been determin...