Sabrina Asteriti, S. Daniele, F. Porchia
Sep 1, 2012
Citations
2
Influential Citations
8
Citations
Journal
British Journal of Pharmacology
Abstract
Recently, a small molecule (Q94) was reported to selectively block PAR1/Gαq interaction and signalling. Here, we describe the pharmacological properties of Q94 and two analogues that share its benzimidazole scaffold (Q109, Q89). Q109 presents a modest variation from Q94 in the substituent group at the 2‐position, while Q89 has quite different groups at the 1‐ and 2‐positions.