S. Wunderlich, P. Knochel
Dec 21, 2008
Citations
0
Influential Citations
43
Citations
Journal
Chemical communications
Abstract
3,6-Dichloropyridazine undergoes a smooth metallation using (tmp)2Zn.2MgCl2.2LiCl. The resulting bis-organozinc species react with various electrophiles; subsequent functionalization via a second metallation proceeds readily; further reactions with hydrazine lead to highly substituted pyrazolo[3,4-c]pyridazines derivatives.