Y. Han, Y. Choo, Young-chul Lee
Feb 1, 2001
Citations
2
Influential Citations
31
Citations
Quality indicators
Journal
Archives of Pharmacal Research
Abstract
Three varieties of methyl citrate and 1-methyl malate were isolated from the fruits ofOpuntia ficus-indica var.saboten Makino throughin vitro bioassay-guided isolation for the inhibition on monoamine oxidase(MAO). The IC50 values for MAO-B of 1-monomethyl citrate, 1,3-dimethyl citrate, trimethyl citrate and 1-methyl malate were 0.19, 0.23, 0.61 and 0.25 mM, respectively. However, on MAO-A, their inhibitions showed only marginal activity.